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It is a modified version of human glucagon-like peptide-1 (GLP-1), a natural hormone that plays a key role in glucose-dependent insulin signaling and metabolic regulation

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Hiromichi Wakui has received research supports from AstraZeneca, Otsuka Pharmaceutical, and Kaneka Corporation, and honoraria from AstraZeneca, Otsuka Pharmaceutical, Kaneka Corporation, Kyowa Kirin, Sanwa Kagaku, Chugai Pharma, Kowa, Otsuka Pharmaceutical, Novartes, Mitsubishi-Tanabe Pharma, Bayer, and Daiichi-Sankyo Pharma

During a water fast, the body has no choice but to burn stored fat for energy, leading to weight loss