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Acidosis drives the reprogramming of fatty acid metabolism in cancer cells through changes in mitochondrial and histone acetylation

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Adults with a BMI of 30 kg/m or higher-or at least 27 kg/m with weight-related comorbidities-who have not succeeded with lifestyle changes alone and who do not have contraindications such as heart disease, uncontrolled hypertension, glaucoma, hyperthyroidism, pregnancy, or a history of drug abuse

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This reaction can occur because the peptide shares structural similarities with human growth hormone, making certain batches more sensitive to pH levels