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VSV: Total supernatant volume, 1 mL VRV: Supernatant volume added into the reaction system, 20 L=0.02 mL W: Sample weight, g

Gut bacteria ferment fiber at the end of the colon, producing gas as a by-product

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it demonstrated preclinical efficacy (80), progressed to first in human testing, and showed activity in Ras driven models, including combinational benefit with platinum therapy (81, 82)

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