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ICIs provide benefit in terms of improvement in overall survival1 and durable response rates for a variety of cancer patients, however the vast majority2 of patients who receive these therapies experience immune-related adverse events (irAEs)

When dopaminergic activity increases in the evening hours, falling asleep becomes harder

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We first tested Complex I (CI) activity as the entry point for ETC flux, using a commercial activity assay (Fig

Glutathione neutralizes these reactive molecules, helping reduce oxidative stress