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About this article Cite this article Zou, Z., Sun, ML., Wang, K

Conclusion GLP-1 medications represent a promising advancement in the field of weight loss and metabolic health

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The direct biological actions of native bioactive forms of GLP-1 are mediated by the activation of the GLP-1 receptor, which belongs to the family B of the G-protein-coupled receptors (GPCRs) [1,4,7,9]

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GLP-1 RAs are increasingly recommended by current guidelines as preferable treatments in these groups, and our mechanistic studies on inflammatory pathways reinforce and validate these recommendations