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Viral proteins as well as host damage-associated molecular patterns, that accumulate following cellular stress during viral infection, were linked to TLR4 activation, with uncontrolled TLR4 activation being associated with severe disease (Olejnik et al., 2018)

While it may affect the same COX enzymes that NSAIDs target, it doesn't bind to them in the same way

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Gene expression was normalized against the internal control gene GAPDH (glyceraldehyde 3-phosphate dehydrogenase)

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