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This section also explores the distinct yet interconnected roles of central glial cells, such as microglia and astrocytes, and the broader peripheral immune system in amplifying the inflammatory cascade that characterizes EDC

Additionally, curcumin has anti-inflammatory and immunomodulatory effects on UC, which is related to its ability to regulate the function of DCs and Treg/Th cells [265, 266, 268]

Patients tolerated UPT well during induction and maintenance therapies, and there were no new safety risks [180, 181]

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