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suggested that HQ is a tyrosinase substrate with a poor activity due to the inability to transform met -tyrosinase to oxy -tyrosinase on its own 26

The Journal of Neuroscience: The Official Journal of the Society for Neuroscience, 31(46), 1655616560

doi: 10.3748/wjg.v31.i10.100194 42 GuoRLiYSongQHuangRGeXNietoNet al

The two sequential ATP-dependent reactions by which glutathione is synthesized inside cells, with the enzyme catalyzing the reaction and the number of ATP molecules required for the reaction to occur, displayed above and below the arrows respectively

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doi: 10.1097/WOX.0b013e3182439613 61 WangSGallimorePJLiu-KangCYeungKCampbellSJUtingerBet al