Always consult with a healthcare professional before making changes to your medication regimen
Every single one of the genetic combinations she lists below should be able to tolerate B12 in the form of Hydroxy B12 (and this is why our methylation protocol suggests Hydroxy B12 as the B12 form to begin with): Folks with multiple COMT mutations tend to do very well with Hydroxy B12 (it helps mop up excess peroxynitrites which can cause problems) Folks with MTR & MTRR mutations may do well with methylcobalamin & adenosylcobalamin supplementation And Dr
Avoid recreational drug use
Last reviewed: June 12, 2026 Last updated: June 12, 2026 Written by: Jay Hastings, CEO of PlexusDx Jay Hastings is the CEO of PlexusDx, a precision health company focused on genetic testing, blood biomarker insights, and personalized wellness recommendations
Ghrelin and its receptor, GHS-R1a, were identified in osteoblasts, and ghrelin promoted both proliferation and differentiation
Note: GLP-1 brands include Victoza, Trulicity, Saxenda, Ozempic, Rybelsus, Wegovy, and Mounjaro Source: IQVIA LAAD pharmacy claims, PlanTrak projected pharmacy claims