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Understanding the fatigue that can accompany GLP-1 treatment also requires blood work context, since deficiency-driven fatigue looks different from adjustment-phase fatigue

In mice that were subjected to streptozotocin (A chemical that destroys beta cells), treatment with Exendin-4 (A GLP1R agonist) leads to an increased number of insulin-producing cells in the pancreas, compared to control mice (Xu et al, 2006)

Med Hypotheses 63(5):834837 Ashida H, Saito Y, Kojima C, Yokota A (2008) Enzymatic characterization of 5-methylthioribulose-1-phosphate dehydratase of the methionine salvage pathway in Bacillus subtilis

doi: 10.1016/j.peptides.2019.170233

Warrington, T

doi:10.1007/978-3-642-35951-4_946-1 16