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The authors assessed volunteers in both supine and lateral positions with gastric ultrasound and then performed a second ultrasound 2 hours after approximately 350 mL of water intake

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Upon receptor activation, intracellular signaling cascades including the phosphoinositide 3-kinase (PI3K)/AKT pathway and the mitogen-activated protein kinase (MAPK/ERK) pathway are activated, influencing cellular metabolism, protein synthesis, cell-cycle progression, and tissue remodeling