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Their metabolic health markers, such as blood sugar and cholesterol, also returned to levels similar to those before treatment.(3) Another drawback to taking GLP-1 medications is that while they promote weight loss, recently published research shows that approximately 15% to 60% of the loss comes from lean mass.(5, 6) This is very concerning, because preserving muscle mass is crucial for maintaining metabolic rate, overall health, and functionality as we age.(7) The Potential Solution: A Ketogenic Lifestyle A paper by researchers at Virta Health, published in February 2024, suggests that a ketogenic diet may help people maintain their weight loss after transitioning off GLP-1 medications.(8) The study compared two groups of type 2 diabetes patients following a ketogenic diet: one group continued GLP-1 therapy, and the other group stopped the medication
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In other words, these supplements are not a direct replacement for prescription weight loss medications like Ozempic, but they can help support your bodys natural GLP-1 production
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A limitation with the use of GLUTag cells, as well as other models for epithelial cells, is that the cells have lost their polarization, which may affect the amino acid sensing mechanisms, as different amino acid transporters are situated on the apical compared to the basolateral membrane [28]
