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Lysosomal acid lipase deficiency (LAL-D): With this genetic condition, you cant produce an enzyme called lysosomal acid lipase, which helps your body break down fats and cholesterol in your cells

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Acknowledgements We are grateful for the willingness of the patients to participate in the GCKD study

Extending the MS 3 performance using synchronous precursor selection (SPS) boosts the sensitivity needed to reach the same LOQ using more cost-effective sample preparation steps as MS 2 acquisition with SPE