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Therapeutically, this raises two complementary possibilities: (1) SQOR-high tumors may exhibit enhanced mitochondrial ferroptosis resistance through maintained CoQ 10 H 2 and sulfur-based RTAs and (2) tumors with altered sulfur/selenium metabolism may reveal synthetic vulnerabilities when SQOR-linked defense is impaired
Ma, Shuguang [Xenobiotica, 2022, vol
Brown GM
The Gerontologist, 55 (6), 901
Hursitoglu, O
B12 deficiency is also more common in people who are over the age of 50, who are pregnant, or who have medical conditions that inhibit nutrient absorption, such as celiac disease and Crohns disease
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