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[11] The compound promotes angiogenesis and as a result has some concerns over cancer promotion

The extreme intensity and unpredictability of the pain associated with trigeminal neuralgia can lead to emotional distress, anxiety, depression, sleep disturbances, and social withdrawal

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If the advisory panel votes against reclassification, or if a future administration revisits the question, these compounds could return to Category 2 restriction

This can stimulate angiogenesis at sites of tissue disruption in animal models ERK1/2 activation: Studies in preclinical settings have observed activation of extracellular signal-regulated kinases

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