All mice were housed under a 12 h light/dark cycle, with the temperature consistently maintained between 18 C and 23 C and the humidity kept at ~50%
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Funding The project was supported by the National Key R&D Program of China through grant 2022YFC3601305 awarded to QT, grant 2022YFA0806400 awarded to YW, and Jilin Province Special Project of Medical and Health Talents through grant 3D5214505428 awarded by QT