There might be a similar interpretation of the therapeutic effect in the crushed rats (crushed gastrocnemius complex, 0.727 Ns/cm 2 , 2 cm proximal to the Achilles tendon insertion) [45,46]
That is, dihydroorotate (DHO) is oxidized to orotate (OA), and at the same time electrons are transferred to ubiquinone in the inner membrane of mitochondria, which is reduced to dihydroubiquinone [51]
In men, the Q1 group exhibited the highest mean values for SBP, DBP, serum glucose, total cholesterol, triglyceride, and CRP levels, whereas the Q4 group possessed the highest mean value for serum HDL cholesterol and total energy intake
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Last reviewed: April 2026
It helps raise good cholesterol (HDL) while reducing bad cholesterol (LDL)