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Evaluation by different mechanisms of the protective effects of vitamin B12 on methotrexate nephrotoxicity

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Monolayers of hiPSC-derived endothelial cells from Alzheimer's patients with PSEN1 and PSEN2 mutations, differentiated with a chemically defined medium, possessed a low TEER, reduced expression of claudin-5, occludin, and ZO1 protein, and impaired glucose transport (Raut et al., 2021)

doi:10.1186/s12974-020-01786-5 Aragon IM, Herrera-Imbroda B, Queipo-Ortuno MI, et al