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Dextran sulfate sodium (DSS)-induced colitis caused amyloid plaque accumulation, compromised glymphatic clearance and increased infiltration of gut-derived T-cells, and triggered cortical and hippocampal degeneration mediated by NACHT-LRR and PYD-containing protein 3 (NLRP3) inflammasome expression (He et al., 2021)

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The metabolites and proteins with statistically significant associations with vital parameters are presented in tables with the effect estimate, standard error, test statistic, and p -value from the regression

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