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When these two pathways are activated simultaneously, the effect is multiplicative: GHRH increases the amount of GH released per cell, and GHRP increases the number of responding cells

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Our previous study found that dapagliflozin may act on the rostral ventrolateral medulla (RVLM) and affect the sympathetic outflow of sympathetic preganglionic neurons to the intermediolateral nucleus of the spinal cord (IML), thereby promoting parasympathetic activity