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Glutathione works on the skin pigment production by inhibiting tyrosinase, and enzyme involved in making melanin

Enhanced expression of GSH metabolism enzymes including glutathione peroxidases, gamma-glutamyl cysteinyl synthetase (gamma-GCS), glutathione S-transferases (GST), and ABC-family membrane transport proteins including the multidrug resistance-associated protein (MRP) were all documented to play prominent roles in cellular resistance to oxidative stress

At these higher levels, the peptide exerts potent biological signals that bypass the bodys usual feedback loops

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J Exp Ther Oncol