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Coste J, et al

Specifically, in the group of patients prescribed semaglutide for weight loss, 6.7% developed NAION compared to just 0.8% of those on other treatments

Whats unclear is how regulators are allowing this, PhRMA said in a Feb

For example, it can increase the phagocytic capacity of macrophages in the testis, inhibit the p38 MAPK pathway, and promote testosterone secretion by Leydig cells, thereby reducing inflammation (76)