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CNS Spectrums 22(5):385-387
There are numerous reasons for an altered microglial secretory profile in aging, but one specific to white matter regions could be an increase in myelin debris that cannot be efficiently cleared/metabolized by microglia, resulting in cellular stress (Safaiyan et al., 2016)
Reported effects are mild and transient: Localized irritation or redness at injection site, Mild fatigue or transient headache during initial days, Rare gastrointestinal upset (nausea, stomach discomfort)
[DOI] [PMC free article] [PubMed] [Google Scholar] 69
Some studies have linked long-term consumption of glutathione to lower zinc levels
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