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In other class III fusion proteins, structural differences have been shown to allow neutralization by antibodies specific to the prefusion conformation

J Am Diet Assoc 1995;95:666-670

Such interaction between metformin and oral cimetidine has been observed in normal healthy volunteers in both single- and multiple-dose metformin-cimetidine drug interaction studies, with a 60% increase in peak metformin plasma and whole blood concentrations and a 40% increase in plasma and whole blood metformin AUC

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The effect of regularly dosed paracetamol versus no paracetamol on renal function in plasmodium knowlesi malaria (PACKNOW): Study protocol for a randomised controlled trial