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In human hepatocarcinoma HepG2 cells, ABAP-generated peroxyl radicals easily convert DCFH that is trapped within the cells to fluorescent dichlorofluorescein (DCF)

PMID 16417305

Vasculogenic ED Researchers have long noted the common co-occurrence of ED and cardiovascular or metabolic diseases

Obviously, this ferroptosis mechanism induced by Erastin is clearly distinct from the iron overloaddriven ferroptosis observed in EMS tissues, both are based on ROS-induced lipid peroxidation and its damage to the cell membrane, leading to cell death, but the driving mechanisms differ

The OGDHc and related OADHc have an intrinsic capacity to remove acyl-lipoyl modifications, as these intermediates are part of the catalytic function of the complexes

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