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Its therapeutic potential extends beyond managing hyperuricemia, demonstrating efficacy as a URAT1 and GLUT9 inhibitor, especially in cases of renal impairment

different studies have found controversial results (245)

3 Results 3.1 Nitazoxanide improved liver function in rats with MTX-hepatotoxicity As depicted in Figure 2, an impaired liver function was observed in the MTX group compared to CTRL, as indicated by significantly elevated serum liver enzymes

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Angiotensin II up-regulates sodium-glucose co-transporter 2 expression and SGLT2 inhibitor attenuates Ang II-induced hypertensive renal injury in mice