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Psychological and behavioral effects of GLP-1 and GIP agonists in weight loss: a comprehensive review

Although various adverse side effects, including gastrointestinal disturbances, sagging jowls, sulfurous burping and other issues have been reported among GLP-1 users, there has been limited research or reporting about their potential impact on smell and taste perception

This scientific uncertainty, compounded by the drugs unavailability in China, highlights an imperative to explore alternative therapeutic pathways independent of the leptin-melanocortin system

Improvement in hyperpigmentation up to 194% when used with a complete routine

Both SR and XL typically show some effects within 2 weeks of starting treatment, though full benefits may take 4-6 weeks

Subsequently, we used Pomc -hrGFP mice to perform whole-cell patch-clamp recordings of fluorescently labeled POMC neurons from acute hypothalamic slices that contained areas of the ARH (Fig