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Patients with GERD or Gastroparesis The SNAC absorption enhancer can irritate stomach lining and worsen: Gastroesophageal reflux disease Chronic gastritis Delayed stomach emptying Peptic ulcers Injectable options dont have these issues

10.1080/10408360091174231 Krijgsheld KR, Glazenburg EJ, Scholtens E, Mulder GJ: The oxidation of L- and D-cysteine to inorganic sulfate and taurine in the rat

Dose-dependent fatty acid-induced GLP-1 secretion is evident with -linolenic acid (C18:3), docosahexanoic acid (C22:6), and palmitoleic acid (C16:1), oleic acid (C18:1), stearic acid (C18:0), and octanoic acid (C8:0) [251] are less effective

Basu, A., Charkoudian, N., Schrage, W., Rizza, R

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O., Zimmer, M