Table 3 summarises key studies documenting changes in gut microbiota associated with ALD, particularly focusing on bacterial species reported in more than two studies.145 146 149172 Table 3 Immune cells within the gut, including dendritic cells, innate lymphoid cells, MAIT cells and T cells, form the immunological barrier.8 These cells secrete antimicrobial peptides and IgA, which play crucial roles in maintaining tolerance to commensal microbes and defending against pathogenic organisms.173 Chronic alcohol consumption impairs this immune function
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The effects of UA in fructose metabolism and potential deleterious metabolic effects have been earlier discussed (,)
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Sybil Keefer 2004 Eastern Redbud 23