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Stroke 37:524530 Roe CR, Millington DS, Maltby DA, Bohan TP, Hoppel CL (1984) l-Carnitine enhances excretion of propionyl coenzyme A as propionylcarnitine in propionic acidemia

The typically assumed GPCR activation mechanism posits that the agonist binding induces conformational changes of the receptor towards active state, resulting in the opening of an intracellular cavity, where G protein binds 3,4

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