Semaglutide GLP-1 is a medication administered on a weekly basis, subcutaneously, to aid in weight loss
Genetic variants in the GLP1-related genes are linked to obesity and diabetes
The magnitude of weight loss reported in the STEP trials offers the potential for clinically relevant improvement for individuals with obesityrelated diseases
Common symptoms of this disease include yellowing of the skin (jaundice), abdominal pain, fever, nausea and vomiting
Most GLP-1 receptor agonists carry a boxed warning for thyroid C-cell tumors and are contraindicated in patients with personal or family history of medullary thyroid carcinoma or Multiple Endocrine Neoplasia syndrome type 2
What makes this medication especially interesting is the shift toward oral GLP-1 therapy, offering another option for patients who may prefer not to use injectable treatments