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When to Contact Your Provider Contact your healthcare provider immediately if you experience: Diarrhea lasting more than 3 days Daily diarrhea throughout the week (not just after injection) Signs of dehydration (dizziness, dry mouth, dark urine, confusion) Severe abdominal pain or cramping Blood or mucus in stool Fever above 101F (38.3C) Significant weight loss Unable to keep fluids down Quick Tips Diarrhea in the first 1-2 days after injection is normal for some patients Track bowel movements to identify patterns Stay near a bathroom if you experience post-injection diarrhea Use barrier cream if experiencing frequent bowel movements Most patients find diarrhea improves after dose stabilization Never ignore persistent diarrheadehydration is dangerous References Nauck MA, et al

The agency is in the process of reviewing comments for consideration in issuing a final rule, the FDA spokesperson said

According to Ohio State, smaller meals, regular protein, and steady hydration can be especially helpful when GLP-1 appetite and tolerance are off

Materials 9 , 225 (2016)

Melatonin synthesis in the epiphysis was assessed by quantifying the excretion of 6-sulfatoxymelatonin in urine

It's the only independent proof that what's in the vial matches what's on the label