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Chronic hyperglycemia contributes to atrial remodeling, fibrosis, and electrical instability

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Pair with Prenatal Antioxidants Such as Vitamin C and Vitamin E to support glutathione recycling

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On an experimental day, cells were washed with Hanks Balanced Salt Solution (HBSS, Gibco/ThermoFisher Scientific) and the respective receptors were labeled with 100 nM HaloTag NanoBRET 618 ligand (Promega Corporation, Fitchburg, WI) in phenol red-free Opti-MEM I reduced serum medium (Gibco/ThermoFisher Scientific) (2 h, 37 C, 5% CO 2 )

Inject both peptides simultaneously for maximum pulse