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Glucose Homeostasis Incretin-driven insulin secretion and glucagon regulation

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The transcripts and activities of ROS scavenging enzymes (SOD/POD/MDHAR) were increased in mutants subjected to cold stress, probably due to the alleviation of ROS-induced oxidative stress, which contributes to the freezing tolerance of the mutants (Weng et al., 2020)

However, slow dose escalation improves tolerability

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