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In 2023, Humphrey and Lawrence emphasized the importance for plastic surgeons to recognize these potential effects, counsel patients before initiating therapy, and consider both surgical and non-surgical interventions to mitigate facial volume loss, sagging, and premature aging [86]

People using Zoloft for depression or anxiety symptoms may be asked to track mood, sleep, appetite, energy, agitation, and any new or worsening thoughts of self-harm

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doi: 10.1016/s0031-9384(97)00246-1 87 GreavesMW

Yamamoto, R