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Tolvaptan reduces TKV (Total kidney volume TKV, prognostic biomarker for risk assessment in ADPKD, Fick-Brosnahan et al., 2002) and renal function decline

Albumin-bound fatty acids gain access into the brain by both passive diffusion and protein carrier-mediated transport via FAT/CD36 and FATP1

However, if frequent urination is accompanied by burning, urgency, or changes in urine appearance, it may indicate infection rather than simple fluid balance

Heart failure (HF) is a clinical syndrome characterised by symptoms and signs caused by structural and/or functional cardiac abnormalities associated with elevated natriuretic peptide levels and/or objective evidence of pulmonary or systemic congestion

GLP-1 patients often reduce food intake

Unveiling the pathogenesis and therapeutic approaches for diabetic nephropathy: insights from panvascular diseases