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However, SNI-challenged mice administered intraplantar injections of 10 g of exendin 939 presented alleviated heat hyperalgesia starting at 1 h postadministration, peaking at 3 h, compared with those in the vehicle-administered group (Fig

Unlike sedative-hypnotics that suppress REM sleep and create dependency, DSIP appears to support natural sleep architecture allowing normal progression through all sleep stages while specifically enhancing the deepest, most restorative phases