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When you put a glucose-lowering drug (Zepbound) and a glucose-raising drug (prednisone) in the same patient, the math doesn't always cancel out cleanly

If you are trying to reach the next level in your fitness goals, Ipamorelin may be the supplement you need to increase muscle mass, stimulate body fat loss and improve overall health

I see a lot of anecdotal reports of anhedonia and I suspect if a patient already has issues with their dopaminergic system, reward motivation, etc, that they might not be the best candidates for GLP-1 agonists for depression treatment as they can cause anhedonia even in low doses by affecting brain reward pathways and blunting dopamine signaling, often reported as emotional flatness

Grondman I, Pirvu A, Riza A, Ioana M, Netea MG