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This leads to reduced macrophage activation and nitric oxide (NO) secretion, offering protective effects to the hepatic sinusoidal endothelium

To protect cells against oxidative damage, organisms have developed self-defense mechanisms, which depend primarily on the availability of antioxidant enzymes and their substrates (oxidants)

N.ErlandsonK

Abstract Glucose-6-phosphate dehydrogenase (G6PD) deficiency is the most common human enzyme defect and one of the most common genetic disorders worldwide, with an estimated 400 million people worldwide carrying a mutation in the G6PD gene that causes deficiency of the enzyme

L.MagliacaneD.SaittaS.LoffredoS.SaijaA.et al

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