glp 1 drugs for cardiovascular health Heart Benefits of GLP-1s Disappear Fast if You Stop Taking The GLP-1 Atrial Fibrillation Risk and

doi.org/10.1007/s00109-016-1488-y Vasireddi, N., et al

Sci Signal 2012

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In a rat model of diabetes-induced testicular dysfunction, liraglutide reduced testicular TGF- and Smad2 mRNA expression levels [26], whilst in HUVECs, liraglutide attenuated high glucose and IL-1-induced TGF- signalling (via inhibition of Smad2 phosphorylation), leading to reduced endothelial-to-mesenchymal transition (EndMT) marker expression [27]