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Nevertheless, the P5-induced increase in [Ca 2+ ] i in CHO-GLP-1R expressing cells was inhibited by the selective Gq inhibitor FR900359 (refs 17, 18

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The long-lasting neuroinflammation leads to sensitization of the CNS, with chronic pain as a consequence (Chen et al., 2018

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A subsequent study analyzed the weight-loss strategies used by the patients in the intensive intervention group and found that weekly self-weighing, regular consumption of breakfast, and reduced intake of fast food were associated with a lower body mass index in overweight patients