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But it works slightly differently than Wegovy and other weight loss injections, including Saxenda

The real gauntlet will be whether those results hold up in a wider population, in the real world, and for longer than a few years

How they work: They mimic the gut hormone GLP-1, which stimulates insulin release in response to food, suppresses glucagon, slows gastric emptying, and reduces appetite

Some patients view these medications as temporary tools to jumpstart weight loss, while others accept them as long-term management for a chronic condition

Some patients need GLP-1 therapy for fat loss

In turn, efferent fibres within the vagus nerve participate in a brain-gut axis to regulate metabolism