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Considering the effects of melatonin on the expression of various collagen types in injured nerves, we next raised the question of how melatonin might influence reorganisation of the extracellular matrix and perhaps the basal lamina around the Schwann cells

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Even in the trial, fibrosis improvement rates were more modest than MASH resolution

It is intraperitoneally injected as it is an effective route for delivering substances in research animals because the peritoneal cavity has a large surface area and is rich with blood supply, allowing for rapid absorption