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Biomedical Research 2009

It directly engages NF-kB signaling, the master inflammatory transcription factor governing expression of IL-6, TNF-alpha, IL-1beta, COX-2, and hundreds of related mediators

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Full Answer: A 2015 study published in the Annals of Clinical and Laboratory Science found that ultrasound-guided intra-articular injections of AOD-9604 significantly improved cartilage regeneration in a rabbit knee osteoarthritis model

It is highly stable in acidic environments, remaining intact for more than 24 hours, which allows it to be administered orally without the need for protective carriers