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When Cas9 is active, the GFP sequence gets cleaved and only the BFP fluorescence is detected

* Correspondence: Qinming Yu, [email protected] Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

The dosage depends on the needs of the patient, though the usual dosage is 1,000 micrograms

This distinction influences efficacy, side effect profiles, and individual response rates across different patient populations

According to the FDA, Foundayo was approved just 50 days after filing 294 days ahead of its scheduled decision date making it the first new molecular entity (NME) approved under the program and the fastest approval of an NME since 2002

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