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Managing gastrointestinal side-effects and preventing treatment discontinuation with GLP-1 therapies GI symptoms are the most common adverse effects of GLP-1 therapies, with nausea, constipation, diarrhea, and vomiting occurring in around 40 % of patients [11,[30], [31], [32]]

In studies , 8.5% of participants taking 0.5 mg of Ozempic weekly experienced diarrhea, while 8.8% of those taking 1 mg weekly reported this side effect

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10.1038/nm0696-699 Nat Med

Omarigliptin: First global approval

The immunoprecipitated proteins were recovered by centrifugation at 14 000 g for 2 min (4 C), washed with ice-cold buffer D, and resuspended in protein sample buffer containing ME