Big picture, this isnt a reason for alarm
The Food and Drug Administration (FDA) approved Wegovy (semaglutide) injection to help adults and children aged 12 years and older with obesity, which is measured as an initial BMI at or above the 95th percentile for age and sex, based on the Centers for Disease Control and Prevention growth charts
46 The data from these mice, similar to those subjected to a transient increase in gut permeability, suggest that under conditions of compromised gut permeability, there are adaptive immune components activated in response to the hyperactivated immune system, and that these immune compensatory mechanisms may help provide resistance to colitis
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d'Errico A, Taioli E, Chen X
They can also be used to help with mood regulation, digestion, and other benefits