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Unopened lyophilized powder is more forgiving and can tolerate brief room-temperature periods, but a reconstituted vial needs consistent refrigeration and should be used within 28 days, the window supported by bacteriostatic water's antimicrobial preservative

BMC Musculoskelet

Lemari CA, Schiffrin EL

A short non-diabetic cohort measured a flat 2.5 mg dose for about four weeks and found weight and insulin-resistance movement (about -4.7% body weight). That makes "2.5 mg has no data" outdated

If you have a B12 deficiency you will be lucky to get the best treatment recommended as it seems to me that GPs pick and choose based on outdated understanding of research and good practice

Will you refuse to treat me if I am not a good candidate