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doi:10.1007/s11481-012-9426-4 19

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Furthermore, while we and others previously showed that GIPR agonism decreases body weight and food intake via Gip r signalling in GABAergic neurons 14,19 , here we found that the ability of GIPR antagonism to amplify GLP-1-induced weight loss does not depend on the presence of GIPR in GABAergic neurons

Why peptides are different from biologics Biologics like adalimumab, secukinumab, and ustekinumab are large monoclonal antibodies that block specific cytokines with extraordinary precision