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The primary endpoint was the incidence of MACEs (cardiovascular death, non-fatal myocardial infarction, non-fatal stroke, hospitalization for heart failure)

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With appetite suppression, theres potential for insufficient protein intake, and if so, the body may break down its own muscle tissue to meet its needs, said Chad Harris, Ph.D., chair of the Department of Exercise and Sport Sciences at Metropolitan State University of Denver

The relation between inadequate zinc intake and raised insulin concentration in blood was also noticed in adolescents [28]